发明名称 |
COMPOUND FOR TREATING CLOSTRIDIUM DIFFICILE |
摘要 |
The invention relates to compounds, compositions and polymers comprising a first component adapted to promote germination of Clostridium difficile (C.diff) and a second component which acts as an antimicrobial agent. Said compounds, compositions and polymers are useful for destroying C.diff where conventional antimicrobial agents are unsuccessful. The compositions can be formulated as coating or materials which actively destroy C.diff which come into contact with it. The germination promotion is induced by bile salts. The invention also relates to the use of such materials as a treatment for C.diff associated diseases and toxic megacolon. |
申请公布号 |
WO2016083819(A1) |
申请公布日期 |
2016.06.02 |
申请号 |
WO2015GB53614 |
申请日期 |
2015.11.26 |
申请人 |
ASTON UNIVERSITY |
发明人 |
RATHBONE, DANIEL LEE;WORTHINGTON, TONY;AL-MALAIKA, SAHAR;HIRD, MATTHEW JUSTIN;QUAYLE, ALEXANDRIA ROSE |
分类号 |
A61K47/48;A61P31/04 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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