发明名称 SELF-EMULSIFYING COMPOSITION OF OMEGA3 FATTY ACID
摘要 A self-emulsifying composition contains: 70 to 90% by weight in total of one or more compounds selected from the group consisting of ω3 polyunsaturated fatty acids and their pharmaceutically acceptable salts and esters; 1 to 29% by weight of an emulsifying agent selected from among a polyoxyethylene sorbitan fatty acid ester, a sorbitan fatty acid ester, a glycerin fatty acid ester and a polyoxyl castor oil; and 0.5 to 6% by weight of water when the composition is defined to be 100% by weight as a whole. The self-emulsifying composition is excellent in self-emulsifying property, composition dispersibility, emulsion stability, and absorbability, is free from ethanol and polyhydric alcohols or only has such an alcohol added thereto at a reduced concentration, and is useful for foods and pharmaceuticals.
申请公布号 US2016151319(A1) 申请公布日期 2016.06.02
申请号 US201414905520 申请日期 2014.07.17
申请人 MOCHIDA PHARMACEUTICAL CO., LTD. 发明人 KIMURA Shigeru;ITO Hiromitsu;FUJII Hirosato;YAMAGATA Motoo
分类号 A61K31/202;A61K47/10;A61K9/48;A61K47/14 主分类号 A61K31/202
代理机构 代理人
主权项 1. A self-emulsifying composition comprising, when the self-emulsifying composition is defined to be 100% by weight as a whole, a) 70 to 90% by weight of at least one compound selected from the group consisting of ω3 polyunsaturated fatty acids and their pharmaceutically acceptable salts and esters, b) 0.5 to 6% by weight of water, and c) 1 to 29% by weight of an emulsifying agent including either i) a polyoxyethylene sorbitan fatty acid ester orii) at least two members selected from the group consisting of a sorbitan fatty acid ester, a glycerin fatty acid ester and a polyoxyethylene castor oil, or 1 to 29% by weight of an emulsifying agent including i) a polyoxyethylene sorbitan fatty acid ester andii) at least one member selected from the group consisting of a sorbitan fatty acid ester, a glycerin fatty acid ester and a polyoxyethylene castor oil, wherein d) content of ethanol is up to 4% by weight of the whole composition, and e) content of polyhydric alcohol is up to 4% by weight of the whole composition.
地址 Tokyo JP