发明名称 |
SELF-EMULSIFYING COMPOSITION OF OMEGA3 FATTY ACID |
摘要 |
A self-emulsifying composition contains: 70 to 90% by weight in total of one or more compounds selected from the group consisting of ω3 polyunsaturated fatty acids and their pharmaceutically acceptable salts and esters; 1 to 29% by weight of an emulsifying agent selected from among a polyoxyethylene sorbitan fatty acid ester, a sorbitan fatty acid ester, a glycerin fatty acid ester and a polyoxyl castor oil; and 0.5 to 6% by weight of water when the composition is defined to be 100% by weight as a whole. The self-emulsifying composition is excellent in self-emulsifying property, composition dispersibility, emulsion stability, and absorbability, is free from ethanol and polyhydric alcohols or only has such an alcohol added thereto at a reduced concentration, and is useful for foods and pharmaceuticals. |
申请公布号 |
US2016151319(A1) |
申请公布日期 |
2016.06.02 |
申请号 |
US201414905520 |
申请日期 |
2014.07.17 |
申请人 |
MOCHIDA PHARMACEUTICAL CO., LTD. |
发明人 |
KIMURA Shigeru;ITO Hiromitsu;FUJII Hirosato;YAMAGATA Motoo |
分类号 |
A61K31/202;A61K47/10;A61K9/48;A61K47/14 |
主分类号 |
A61K31/202 |
代理机构 |
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代理人 |
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主权项 |
1. A self-emulsifying composition comprising, when the self-emulsifying composition is defined to be 100% by weight as a whole,
a) 70 to 90% by weight of at least one compound selected from the group consisting of ω3 polyunsaturated fatty acids and their pharmaceutically acceptable salts and esters, b) 0.5 to 6% by weight of water, and c) 1 to 29% by weight of an emulsifying agent including either
i) a polyoxyethylene sorbitan fatty acid ester orii) at least two members selected from the group consisting of a sorbitan fatty acid ester, a glycerin fatty acid ester and a polyoxyethylene castor oil, or 1 to 29% by weight of an emulsifying agent including
i) a polyoxyethylene sorbitan fatty acid ester andii) at least one member selected from the group consisting of a sorbitan fatty acid ester, a glycerin fatty acid ester and a polyoxyethylene castor oil, wherein d) content of ethanol is up to 4% by weight of the whole composition, and e) content of polyhydric alcohol is up to 4% by weight of the whole composition. |
地址 |
Tokyo JP |