发明名称 |
Synthetic promoters for CHO cells, methods of producing synthetic promoters using transcription factor binding site modules |
摘要 |
CHO cell-specific synthetic promoter constructs for expressing recombinant proteins, a library of promoter constructs thereof, and a method for producing the promoter constructs. The promoter constructs enable precise control of recombinant gene transcription over three orders of magnitude, with the top expressing promoters capable of double the transcriptional activity of the CMV promoter. |
申请公布号 |
AU2014356396(A1) |
申请公布日期 |
2016.06.02 |
申请号 |
AU20140356396 |
申请日期 |
2014.11.28 |
申请人 |
UCB BIOPHARMA SPRL |
发明人 |
JAMES, DAVID CAMERON;BROWN, ADAM JOHN |
分类号 |
C12N15/85 |
主分类号 |
C12N15/85 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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