发明名称 |
THERAPEUTIC FORMULATION AND METHODS OF TREATMENT |
摘要 |
The present disclosure relates pharmaceutical formulations comprising hydralazine in the treatment of eye diseases and conditions with the formulations. The present disclosure also related to methods of preparing the pharmaceutical formulations. |
申请公布号 |
US2016151368(A1) |
申请公布日期 |
2016.06.02 |
申请号 |
US201615018620 |
申请日期 |
2016.02.08 |
申请人 |
MacuCLEAR, Inc. |
发明人 |
Lewis Pamela A.;Woller William H. |
分类号 |
A61K31/502;A61K9/08;A61K9/00 |
主分类号 |
A61K31/502 |
代理机构 |
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代理人 |
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主权项 |
1. An ophthalmic composition, comprising:
a pharmaceutically active drug comprising hydralazine in an amount between about 0.02-2 wt %; an acetate buffer solution having pH of between 3.9-4.5 in an amount between 8-12 wt %; propylene glycol in an amount between 0.5-2 wt %; sodium chloride in an amount between 0.25-1 wt %; methylparaben in an amount between 0.015-0.06 wt %; benzalkonium chloride in the form of a 50% solution, present in an amount between 0.01-0.04 wt %; and edetate disodium in an amount between 0.008-0.030 wt %; wherein said composition has a pH of between 4.0-4.4. |
地址 |
Richardson TX US |