| 发明名称 |
INFLUENZA VIRUS-NEUTRALIZING ANTIBODY AND SCREENING METHOD THEREFOR |
| 摘要 |
Provided is an anti-influenza virus antibody that exhibits neutralizing activity beyond the barrier of the two groups of influenza viruses categorized according to the conservativeness of hemagglutinin amino acids, a method of producing the same, and a test method for determining whether the subject carries the neutralizing antibody. |
| 申请公布号 |
US2016152692(A1) |
申请公布日期 |
2016.06.02 |
| 申请号 |
US201615017246 |
申请日期 |
2016.02.05 |
| 申请人 |
Fujita Health University ;The Research Foundation for Microbial Diseases of |
发明人 |
KUROSAWA Yoshikazu;IBA Yoshitaka;OHSHIMA Nobuko;OKUNO Yoshinobu |
| 分类号 |
C07K16/10 |
主分类号 |
C07K16/10 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of passive immunotherapy for influenza comprising administering an effective amount of an antibody to a mammalian or avian subject that has been infected, or can get infected, with influenza virus, wherein the antibody is an isolated antibody comprising a heavy chain variable region comprising SEQ ID NO:15 and a light chain variable region comprising SEQ ID NO:26, whereby the antibody binds influenza virus HA. |
| 地址 |
Aichi JP |
