发明名称 POWDER MIXTURES FOR ANTIBIOTIC DRY SYRUP FORMULATIONS
摘要 The present invention provides a pharmaceutical formulation prepared as dry syrups representing mere powder mixtures of beta-lactam antibiotics as active pharmaceutical ingredients and excipients without applying any other process steps than simple mixing of dry powder, whereby the pharmaceutical formulation combines two essential properties for processability and dosability: good flowability and high stability against segregation.
申请公布号 US2016151501(A1) 申请公布日期 2016.06.02
申请号 US201414901950 申请日期 2014.07.08
申请人 Sandoz AG 发明人 Schelere Stefan;Raneburger Johannes;Schwarz Franz Xaver;Kern Florian
分类号 A61K47/36;A61K31/43;A61K9/00;A61K47/14;A61K47/12;A61K31/546;A61K47/02 主分类号 A61K47/36
代理机构 代理人
主权项 1. Formulation of an antibiotic dry syrup preparation prepared as a powder that combining good flowability and high segregation stability containing the following components:a beta-lactam antibiotic;80.0 to 95.0wt %powdered sugar;up to 1.0wt %a preservative; andup to 2.0wt %silicon dioxide.
地址 Basel CH