发明名称 |
MODIFIED VARIABLE DOMAIN MOLECULES AND METHODS FOR PRODUCING AND USING THEM B |
摘要 |
The present disclosure provides an isolated, engineered or non-naturally occurring protein comprising an antibody light chain variable domain (VL) which may comprise at least one negatively charged amino acid positioned between residues 49 to 56 according to the numbering system of Kabat, the protein capable of binding specifically to an antigen. |
申请公布号 |
EP2699597(B1) |
申请公布日期 |
2016.06.01 |
申请号 |
EP20120774201 |
申请日期 |
2012.04.19 |
申请人 |
GARVAN INSTITUTE OF MEDICAL RESEARCH |
发明人 |
CHRIST, DANIEL;DUDGEON, KIP;ROUET, ROMAIN |
分类号 |
A61K49/00;C07K1/22;C07K16/18;C07K16/24;C07K16/32;G01N33/53 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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