发明名称 |
SYNTHESIS OF RESORCYLIC ACID LACTONES USEFUL AS THERAPEUTIC AGENTS |
摘要 |
Disclosed are macrocyclic compounds of formulae I, I′, II, II′, III, III′, IV, and V, which are analogs of the pochonin resorcylic acid lactones, pharmaceutical compositions comprising the compounds, and methods and uses comprising the compounds for the treatment of diseases mediated by kinases and Heat Shock Protein 90 HSP90. |
申请公布号 |
EP2242359(B1) |
申请公布日期 |
2016.06.01 |
申请号 |
EP20090702521 |
申请日期 |
2009.01.15 |
申请人 |
UNIVERSITÉ DE STRASBOURG;WINSSINGER, NICOLAS;BARLUENGA, SOFIA;KARPLUS, MARTIN |
发明人 |
WINSSINGER, NICOLAS;BARLUENGA, SOFIA;KARPLUS, MARTIN |
分类号 |
A01N31/14;A61K31/02;C07D313/00;C07D405/12;C07D405/14 |
主分类号 |
A01N31/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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