发明名称 SYSTEM AND METHOD FOR THE COMPUTATIONAL PREDICTION OF EXPRESSION OF SINGLE-GENE PHENOTYPES
摘要 In accordance with an embodiment of the invention, a system and method is provided for determining a probability of a progeny having one or more phenotypes Phj each associated with a single gene Qj. A score sip may be assigned to each allele hip at a plurality of genetic loci (i) in a haploid genome profile Hp of a parent (p). A plurality (Nj) of the alleles hkp (k=1, . . . , Nj) associated with the gene Qj may be identified. The scores sip may be mapped or indexed to gene-specific scores ŝj,kp associated with gene Qj for the plurality of (Nj) alleles hkp. A probability may be computed for altering the gene product from gene Qj in a progeny of the parent (p) to be a function of the gene-specific scores ŝj,kp.
申请公布号 EP2929070(A4) 申请公布日期 2016.06.01
申请号 EP20130859848 申请日期 2013.12.05
申请人 GENEPEEKS, INC. 发明人 SILVER, LEE M.;COHN, ADAM;SILVER, ARI JULIAN
分类号 G06F19/18 主分类号 G06F19/18
代理机构 代理人
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