发明名称 |
IMPROVED METHODS FOR PURIFICATION OF RECOMBINANT AAV VECTORS |
摘要 |
Provided herein are methods for the purification of recombinant adeno-associated virus (rAAV) vectors that can be used for gene transfer and specifically for gene therapy or vaccination. Recombinant AAV vectors of the invention are substantially free of in-process impurities, including production components such as cellular nucleic acids, cellular proteins, helper virus, and media components. |
申请公布号 |
EP2443233(B1) |
申请公布日期 |
2016.06.01 |
申请号 |
EP20100790155 |
申请日期 |
2010.06.16 |
申请人 |
GENZYME CORPORATION |
发明人 |
SHELDON, PAULENE, MCLEAN, QUIGLEY;GAGNON, PETER, S.;NICHOLS, GINA;THORNE, BARBARA, A. |
分类号 |
C12N7/02 |
主分类号 |
C12N7/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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