发明名称 COMPOUND, NUCLEIC ACID, LABELING SUBSTANCE, AND DETECTION METHOD
摘要 The present invention provides a compound represented by the following chemical formula (I); a tautomer or stereoisomer of the compound; or a salt of the compound, the tautomer, or the stereoisomer. In the chemical formula (I), R 1 and R 2 are each a Group 1 element or a protecting group of an amino group and may be identical to or different from each other, or alternatively, R 1 and R 2 together may form a protecting group of an amino group. R 3 is a Group 1 element or a protecting group of a hydroxy group. R 4 is a Group 1 element or -PR 5 R 6 R 7 R 8 (R 5 , R 6 , R 7 , and R 8 are each a Group 1 element, a lone electron pair, a Group 16 element, a Group 17 element, or a protecting group of a phosphorus atom, and may be identical to or different from each other). J is a hydrogen atom or an arbitrary atomic group, A is a hydrogen atom, a hydroxy group, an alkyl group, an aralkyl group, an alkoxy group, an electron-withdrawing group, a silylene group, or a sulfide group, or alternatively, J and A together may form a linker. L is a single bond or a linker (a linking atom or a linking atomic group), the main chain length (the number of main chain atoms) of the linker is arbitrary, L may or may not contain each of C, N, O, S, P, and Si in the main chain, and may or may not contain each of a single bond, a double bond, a triple bond, an amide bond, an ester bond, a disulfide bond, an imino group, an ether bond, a thioether bond, and a thioester bond in the main chain. Z is an atomic group that can form a peptide bond with a labeling compound, or is an atom or atomic group including a label.
申请公布号 EP2894158(A4) 申请公布日期 2016.06.01
申请号 EP20130834990 申请日期 2013.09.03
申请人 KABUSHIKI KAISHA DNAFORM 发明人 HAYASHIZAKI, YOSHIHIDE;SOMA, TAKAHIRO;HANAMI, TAKESHI;KANAMORI, HAJIME;BABA, MASARU
分类号 C07H19/073;C07H19/067;C07H19/10;C07H21/00;C07H21/04 主分类号 C07H19/073
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