| 发明名称 |
TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR (TALE) - LYSINE-SPECIFIC DEMETHYLASE 1 (LSD1) FUSION PROTEINS |
| 摘要 |
Fusion proteins comprising a DNA binding domain, e.g., a TAL effector repeat array (TALE) or zinc finger array, and a catalytic domain comprising a sequence that catalyzes histone demethylation, and methods of use thereof. |
| 申请公布号 |
EP2906602(A4) |
申请公布日期 |
2016.06.01 |
| 申请号 |
EP20130845212 |
申请日期 |
2013.10.11 |
| 申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
JOUNG, JAE KEITH;MENDENHALL, ERIC M.;BERNSTEIN, BRADLEY E.;REYON, DEEPAK |
| 分类号 |
C07K19/00;A61K38/43;C07K14/435;C07K14/47;C12N15/62 |
主分类号 |
C07K19/00 |
| 代理机构 |
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