发明名称 |
Fusion polypeptides, host cells comprising the same and methods of producing the same |
摘要 |
The present invention relates to the field of glycosylation engineering of proteins. More particularly, the present invention relates to nucleic acid molecules, including fusion constructs, having catalytic activity and the use of same in glycosylation engineering of host cells to generate polypeptides with improved therapeutic properties, including antibodies with increased Fc receptor binding and increased effector function. |
申请公布号 |
IL203402(A) |
申请公布日期 |
2016.05.31 |
申请号 |
IL20100203402 |
申请日期 |
2010.01.19 |
申请人 |
GLY CART BIOTECHNOLOGY AG |
发明人 |
|
分类号 |
C07K;A61K38/00;C07K16/28;C07K16/30;C07K16/32;C12N;C12N9/10;C12N9/24;C12N15/62;C12P;C12P21/00 |
主分类号 |
C07K |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|