| 发明名称 | Tetraaza macrocyclic compound, preparation method thereof and use thereof | ||
| 摘要 | Provided are a cross-bridged tetraaza macrocyclic compound of a novel structure that can be used, for example, as a contrast agent for diagnostic imaging or a radiopharmaceutical and a method for preparing the same.;The disclosed tetraaza macrocyclic compound is able to form a stable metal complex at a lower temperature and allows easy conjugation with a bioactive substance or a chemically active substance, when compared to the existing cross-bridged tetraaza macrocyclic compounds. | ||
| 申请公布号 | US9353120(B2) | 申请公布日期 | 2016.05.31 |
| 申请号 | US201514645967 | 申请日期 | 2015.03.12 |
| 申请人 | Kyungpook National University Industry-Academic Cooperation Foundation | 发明人 | Yoo Jeong Soo;Pandya Darpan |
| 分类号 | A61K49/04;A61P35/00;A61P31/00;C07D487/08;A61K51/04;A61K51/08;A61K51/10 | 主分类号 | A61K49/04 |
| 代理机构 | Alston & Bird LLP | 代理人 | Alston & Bird LLP |
| 主权项 | 1. A tetraaza macrocyclic compound represented by Chemical Formula 1 or a pharmaceutically acceptable salt thereof: | ||
| 地址 | Daegu KR | ||