Crystalline maleate salt of (1r*,2r*,4r*)-2-(2-{[3-(4,7-dimethoxy-1 h-benzoimidazol-2-yl)propyl]-methylamino}-ethyl)-5-phenyl-bicyclo [2.2.2]oct-5-ene-2-yl ester of isobutyric acid, a process for its preparation, compositions comprising it and its uses

摘要

The invention relates to crystalline salts of isobutyric acid (1R*,2R*,4R*)-2-(2-{[3-(4,7 -dimethoxy-1H-benzoimidazol-2-yl)-propyl]-methyl-amino}-ethyl)-5-phenyl-bicyclo[2.2.2]oct-5-en-2-yl ester, processes for the preparation thereof, pharmaceutical compositions containing said crystalline salts, and their use as medicaments, especially as calcium channel blockers.