| 发明名称 | Two-photon absorbing compound with methods of synthesis and use | ||
| 摘要 | Disclosed is a compound which is a two-photon absorbing fluorescent substance, a production method for the compound, a fluorescence sensor and molecular probe able to sense various substrates or enzyme activity or the like using the same, and a method of sensing enzyme activity or the like using the same. The disclosed compound can be used as a fluorescence sensor, and can be used in the study and treatment of diseases in which MAO enzymes are involved such as mood disorders using MAO enzyme activity and inhibitor screening. | ||
| 申请公布号 | US9353399(B2) | 申请公布日期 | 2016.05.31 |
| 申请号 | US201314345137 | 申请日期 | 2013.03.21 |
| 申请人 | POSTECH ACADEMY-INDUSTRY FOUNDATION | 发明人 | Ahn Kyo Han;Kim Dokyoung |
| 分类号 | C12Q1/26;C07C255/42;C07D311/92;C07C221/00;C07C223/06;C07C255/43;C07D311/58;C07F7/18;C12Q1/42;C07C253/30 | 主分类号 | C12Q1/26 |
| 代理机构 | Lucas & Mercanti, LLP | 代理人 | Lucas & Mercanti, LLP |
| 主权项 | 1. A compound or a pharmaceutically acceptable salt thereof selected from the group consisting of: wherein, R is selected from the group consisting of vinyl, propargyl, 4-boronato-benzyl, t-butyldimethylsilyl, homoallyl and phosphate. | ||
| 地址 | Pohang-Si, Gyeongsangbuk-Do KR | ||