Composition comprising a diindolylmethane and a retinoid to treat a skin condition

摘要

Provided is a composition for use in treating a skin condition, the composition comprising:
(a) a first component comprising a substituted or unsubstituted diindolylmethane compound; and(b) a second component comprising a substituted or unsubstituted retinoid compound.

主权项

1. A composition comprising:
(a) a first component comprising a substituted or unsubstituted 3,3′diindolylmethane compound and/or a substituted or unsubstituted 2,2′diindolylmethane compound selected from the following structures:wherein, the R groups are independently selected from H, or C1-C6 hydrocarbons; and
(b) a second component comprising a first generation retinoid; wherein the first generation retinoid is selected from the group consisting of: vitamin A, a substituted or unsubstituted retinol, a substituted or unsubstituted retinal, a substituted or unsubstituted tretinoin (retinoic acid or Retin A), a substituted or unsubstituted isotretinoin, and a substituted or unsubstituted alitretinoin; wherein the ratio (mg:μg) of the first and the second component is between 10:3000 and 500:200.