发明名称 Remodeling and glycopegylation of fibroblast growth factor (FGF)
摘要 The present invention relates to mutants of Fibroblast Growth Factor (FGF), particularly FGF-20 and FGF-2 1, which contain newly introduced N-linked or O-linked glycosylation site(s). The polynucleotide coding sequences for the mutants, expression cassettes comprising the coding sequences, cells expressing the mutants, and methods for producing the mutants are also disclosed. Further disclosed are pharmaceutical compositions comprising the mutants and method for using the mutants.
申请公布号 SI2586456(T1) 申请公布日期 2016.05.31
申请号 SI20050032047 申请日期 2005.10.31
申请人 ratiopharm GmbH 发明人 Defrees Shawn
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