Protecting group for indole group, nucleic acid-synthesizing amidite and nucleic acid-synthesizing method

摘要

A protecting group for 1-nitrogen atom of an indole group including a sulfonylethyl carbamate group, wherein the protecting group is represented by the following General Formula (I) and capable of being removed from the 1-nitrogen atom of the indole group in an aprotic solvent:;where R represents an alkyl group, a derivative of the alkyl group, a phenyl group or a derivative of the phenyl group.

主权项

1. A compound comprising a protecting group on a 1-nitrogen atom of an optionally-substituted indole group, thereby comprising a sulfonylethyl carbamate group,
wherein the protecting group is of Formula (I) and is capable of being removed from the 1-nitrogen atom of the indole group in an aprotic solvent: and wherein R is an alkyl group, a substituted alkyl group, a phenyl group, or a substituted phenyl group.