Drug delivery system including laminated structure

摘要

One aspect of the present invention relates to a drug delivery system comprising a layered structure where a drug layer and a biodegradable polymer layer for controlling the release of drugs are alternately laminated. The drug delivery system can easily control an in-vivo drug release rate and a release amount.

主权项

1. A drug delivery system comprising a layered structure in which at least two drug layers and at least one biodegradable polymer layer for drug release control are alternately stacked; and
a biodegradable polymer outer layer surrounding the layered structure, wherein the biodegradable polymer outer layer comprises an opening, wherein the drug delivery system further comprises a polymer cover covering the opening, wherein the biodegradable polymer outer layer, the at least one biodegradable polymer layer for drug release control and the polymer cover each have a different biodegradation rate, and wherein the biodegradation rate of the biodegradable polymer outer layer is lower than the biodegradation rate of the at least one biodegradable polymer layer for drug release control, and the biodegradation rate of the at least one biodegradable polymer layer for drug release control is lower than the biodegradation rate for the polymer cover, wherein one of the at least one biodegradable polymer layer is between each of the at least two drug layers, and wherein the size of the opening encompasses the entire outer surface of the at least one drug layer located proximal to the opening.