发明名称 PRODUCTION METHOD OF SPRAY DRY SOLUTION AND SOLID DISPERSION USING HYPROMELLOSE ACETATE SUCCINATE
摘要 PROBLEM TO BE SOLVED: To improve clogging and elution efficiency caused by undissolved materials, by producing a solid dispersion using a spray dry solution which has high transmittancy and in which the generation of the undissolved materials is remarkably suppressed.SOLUTION: The invention provides a spray dry solution containing at least Hypromellose acetate succinate (HPMCAS) in which molar substitution degree of hydroxy propoxy group is 0.40 or more, a solvent, and a drug. The invention also provides a production method of the solid dispersion comprising at least removing the solvent from this spray dry solution.SELECTED DRAWING: None
申请公布号 JP2016098179(A) 申请公布日期 2016.05.30
申请号 JP20140233774 申请日期 2014.11.18
申请人 SHIN ETSU CHEM CO LTD 发明人 WARASHINA SHOGO;KUSAKI FUMIE;KIKUCHI KAZUKI;OHARA SAKAE;MARUYAMA NAOAKI
分类号 A61K47/38;A61K9/14 主分类号 A61K47/38
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