发明名称 |
Método de cuantificación raman de una sustancia relacionada al cáncer. |
摘要 |
This invention relates to a method for measuring cancer related substances including cancer cell-derived free DNA by Raman spectroscopy. This measuring method is characterized by involving steps for preparing a biochip having a meso-crystal region of silver oxides containing a silver peroxide, adding a blood serum or a biological sample solution dropwise onto the meso-crystal region of said biochip, selectively trapping the cancer-related substances having a positive charge in the sample, irradiating the trapped cancer-related substance with an exciting laser light and detecting a surface enhanced Raman scattering therefrom, wherein cancer diseases are evaluated on the basis of the intensity of the Surface Enhance Raman Scattering (SERS). In the carbon-specific D band and G band in the Raman scattering spectrum, a characteristic peak spectrum of the cancer-related substance can be detected in the proximity of the methyl group characteristic of 2900cm -1 . |
申请公布号 |
CL2015003261(A1) |
申请公布日期 |
2016.05.27 |
申请号 |
CL20150003261 |
申请日期 |
2015.11.06 |
申请人 |
MYTECH CO., LTD.;ITO HOROAKI |
发明人 |
ITO HOROAKI;HASEGAWA YUKI;HASEGAWA KATSUYUKI |
分类号 |
G01N21/65;G01N33/543;G01N33/68 |
主分类号 |
G01N21/65 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|