| 摘要 |
FIELD: biotechnologies.SUBSTANCE: invention relates to biotechnology, specifically to method of treating metabolic disorder in individual by introducing agents, which modulate activity and microRNA expression, and can be used in medicine. Present invention provides method of treating disorders, such as obesity, diabetes or metabolic syndrome, in individual by adding inhibitor expression or activity of miR-378 and/or miR-378*.EFFECT: invention enables effective therapy of wide range of metabolic disorders caused by violation of signal transmission using leptin.9 cl, 19 dwg, 6 ex |
