发明名称 |
COMBINATION OF PI3K INHIBITOR AND C-MET INHIBITOR PI3K C-MET |
摘要 |
The present invention relates to a pharmaceutical combination which comprises (a) a phosphatidylinositol 3-kinase inhibitor or pharmaceutically acceptable salt thereof, and (b) at least one c-Met receptor tyrosine kinase inhibitor or pharmaceutically acceptable salt thereof, for simultaneous, separate or sequential administration for the treatment of a proliferative disease, particularly a c-Met dependent proliferative disease; a pharmaceutical composition comprising such combination; a method of treating a subject having a proliferative disease comprising administration of said combination to a subject in need thereof; use of such combination for the treatment of proliferative disease; and a commercial package comprising such combination. |
申请公布号 |
HK1211476(A1) |
申请公布日期 |
2016.05.27 |
申请号 |
HK20150112283 |
申请日期 |
2015.12.14 |
申请人 |
NOVARTIS AG |
发明人 |
CAPONIGRO, GIORDANO;HUANG, XIZHONG;LEHAR, JOSEPH;WANG, HUI-QIN |
分类号 |
A61K;A61P |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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