COMBINED THERAPY WITH AFUCOSYLATED CD20 ANTIBODY AND mTOR INHIBITOR

摘要

FIELD: biochemistry.SUBSTANCE: invention relates to a combined therapy with afucosylated anti-CD20 antibody and mTOR inhibitor for treating cancer. Disclosed is use of afucosylated humanised anti-CD20 B-Ly1 antibody for preparing a drug for treating B-cell non-Hodgkin lymphoma in combination with mTOR inhibitor, such as temsirolimus or everolimus.EFFECT: invention enables to achieve synergetic anti-proliferative effect in treating cancer.2 cl, 1 dwg, 3 tbl