| 发明名称 |
SPIRO-ISOQUINOLINE-1,4'-PIPERIDINE COMPOUNDS HAVING MULTIMODAL ACTIVITY AGAINST PAIN |
| 摘要 |
The present invention relates to spiro-isoquinoline-1,4'-piperidine compounds having dual pharmacological activity towards both the sigma (σ) receptor and the μ-opiod receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain. |
| 申请公布号 |
WO2016078770(A1) |
申请公布日期 |
2016.05.26 |
| 申请号 |
WO2015EP02332 |
申请日期 |
2015.11.20 |
| 申请人 |
LABORATORIOS DEL DR. ESTEVE, S.A. |
发明人 |
ALMANSA-ROSALES, CARMEN;GARCIA-LOPEZ, MONICA;CAAMANO-MOURE, ANA-MARIA |
| 分类号 |
C07D471/10;A61K31/435;A61K31/438;A61P25/04;C07D471/20 |
主分类号 |
C07D471/10 |
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