| 发明名称 |
TUNABLE FLUORESCENCE USING CLEAVABLE LINKERS |
| 摘要 |
The invention relates to cleavable chemistry in general, and in particular, to tunable fluorescence using cleavable linkers present in fluorochrome-quencher conjugates. |
| 申请公布号 |
US2016145280(A1) |
申请公布日期 |
2016.05.26 |
| 申请号 |
US201414784939 |
申请日期 |
2014.04.21 |
| 申请人 |
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH |
发明人 |
Brenner Sydney;Teo Yin Nah;Tan Pee Mei |
| 分类号 |
C07F9/655;C07H21/04;G01N21/64;C07F7/18 |
主分类号 |
C07F9/655 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. Fluorochrome-quencher conjugate having the structure
F-L1-B-L2-Qwherein
F is at least one fluorochrome; Q is at least one quenching molecule for the at least one fluorochrome, or is another fluorochrome F, or is another fluorochrome other than F; L1 is at least one first cleavable linker molecule; L2 is at least one second cleavable linker molecule; and B is a linking moiety or a target molecule of interest; wherein L1 and L2 are different. |
| 地址 |
Connexis, Singapore SG |
