| 发明名称 |
METHODS AND COMPOSITIONS FOR MODULATING FGF23 LEVELS |
| 摘要 |
The present invention provides compositions, systems, and methods for treating a condition characterized by elevated Fibroblast Growth Factor 23 (FGF23) with a composition comprising: i) an agent that causes an increase in expression of urokinase plasminogen activator (uPA) and/or tissue plasminogen activator (tPA), ii) purified uPA, and/or purified tPA. |
| 申请公布号 |
US2016144001(A1) |
申请公布日期 |
2016.05.26 |
| 申请号 |
US201514949266 |
申请日期 |
2015.11.23 |
| 申请人 |
Northwestern University |
发明人 |
Vaughan Douglas E.;Eren Mesut;Place Aaron T.;Miyata Toshio |
| 分类号 |
A61K38/48;G01N33/74;A61K31/341 |
主分类号 |
A61K38/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating a condition characterized by elevated Fibroblast Growth Factor 23 (FGF23) comprising:
administering and/or prescribing at least one of the following to a subject with a condition characterized by elevated FGF23: i) a first composition comprising an agent that causes an increase in expression of a serine protease selected from urokinase plasminogen activator (uPA) and tissue plasminogen activator (tPA); and ii) a second composition comprising purified uPA, uPA derivative, tPA, and/or a tPA derivative. |
| 地址 |
Evanston IL US |
