发明名称 Procedimiento de desprotección mejorado para la síntesis de compuestos oligoméricos
摘要 Synthetic processes are provided wherein oligomeric compounds are prepared having phosphodiester, phosphorothioate, phosphorodithioate, or other covalent linkages. The oligomers have substantially reduced exocyclic adducts deriving from acrylonitrile or related contaminants.
申请公布号 ES2296372(T5) 申请公布日期 2016.05.26
申请号 ES19990307066T 申请日期 1999.09.06
申请人 Ionis Pharmaceuticals, Inc. 发明人 Ravikumar, Vasulinga T.;Manoharan, Muthiah;Capaldi, Daniel C.;Krotz, Achim;Cole, Douglas L.;Guzaev, Andrei
分类号 C07H21/00;C07H21/04;C07H21/02;C12Q1/68 主分类号 C07H21/00
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