NOVEL BIOMARKER DETECTION WITH MOLECULAR IMPRINTS

摘要

A bio-recognition system is described, where a bio-recognition nanosensor system uses an electropolymerization to produce protein imprints for biomarker recognition. Methods of making a bio-recognition sensor include forming a electropolymer coating on an electrode, binding a target biological structure to the coating to form an imprint, removing the biological structure from the coating, and forming a template that binds a specific biological structure.

主权项

1. A bio-recognition sensor comprising:
(a) a polymer scaffold comprising an electrode, and an electropolymer, wherein said electropolymer forms a coating on said electrode; and (b) a template, wherein said template comprises:
a three dimensional imprint of a biological structure in said electropolymer;
wherein said template comprises chemical moieties that are selective for binding to said biological structure.