Dynamic Lab on a Chip Based Point-Of-Care Device For Analysis of Pluripotent Stem Cells, Tumor Cells, Drug Metabolites, Immunological Response, Glucose Monitoring, Hospital Based Infectious Diseases, and Drone Delivery Point-of-Care Systems

摘要

The invention provides for a novel dynamically configurable point-of-care device for clinical diagnostics and research for analysis of activity associated with pluripotent stem cells, tumor cells, drug metabolites, immunological response, glucose monitoring, cardiovascular diseases, liver cell therapy, cell-cell signaling, epidemic outbreaks, hospital based infectious diseases, pathogens, germ cells, pharmacological compounds, oxidation reduction, microscopy, tomography, flow cytometry, clinical lab testing, and for providing immunoassays, ELISA, electrophoresis, PCR, chromatography, and other laboratory functions. The device comprises a biochemical processing module further comprising a processor and at least one controller, receiving microfluidic elements, sensors, software scripts, an electrically operated interface, flow ports, a user interface, memory, and a communications link, configurable based on analysis of patient data. The invention further provides for multiple-criteria decision analysis for hospital administrators, a wearable device, mobile medical device, molecular electronics configuration, touchscreen recognition, data analytics application, and a drone delivery based point-of-care system.

主权项

1. In accordance with an embodiment, a dynamic point-of-care LOC device for clinical diagnostic and testing and research applications, the device comprising:
a biochemical processing module further comprising:
a processor and at least one controller, at least one receiving module for receiving at least one patient sample, at least one microfluidic element including at least one sensor, at least one first software script for receiving and processing at least one data element from the at least one patient sample, an electrically operated interface, a plurality of flow ports, a user interface, memory, a communications link, wherein the receiving module is operatively configured to receive the at least one patient sample, wherein the sensor is configured to detect the at least one data element from at least one sample, wherein the processing module is communicatively linked to the memory, wherein the processing module is communicatively linked to the sensor for processing the at least one data element from the at least one patient sample, wherein the processing module is further operatively configured to execute one or more second software script based on the at least one first software script for receiving and processing the at least one data element from the at least one patient sample, wherein the processing module is operatively linked to the at least one microfluidic element and the electrically operated interface, wherein the plurality of flow ports is linked to the at least one microfluidic element, wherein the processor and controller are communicatively, wherein at least one or more third software script based on the one or more second software script and the at least one software script is communicated between the processor and controller for executing a control signal linked to the user interface for changing at least one aspect of the configuration of the at least one of: the plurality of flow ports and the at least one microfluidic element based on the at least one data element from the at least one patient sample.