NEW TYPE OF CYTIDINE DERIVATIVE AND APPLICATION THEREOF

摘要

Disclosed are a new type of cytidine derivative, having the general formula (I), and an application thereof. The new type of cytidine derivative of the present invention has a growth inhibitory effect, confirmed by testing, on transplanted colon cancer HCT-116 tumors borne by nude mice; the antitumor activity of the compound of the present invention is high, while the impact on the body weight of the colon cancer HCT-116 tumor-bearing mice, as well as mortality rate data, prove the low toxicity of the compound.