COMPUTATIONAL MICROSCOPY THROUGH A CANNULA

摘要

An imaging system can include an optical fiber and a light source for providing optical stimulation to a region of interest along the optical fiber. A camera can capture emission such as fluorescence resulting from the optical stimulation. A cannula configured for implantation into a subject can be configured to direct the emission from the subject. A mating sleeve coupling the cannula to the optical fiber, and configured to support the camera, can include a dichroic mirror to allow the optical stimulation to pass from the optical fiber to the cannula and to redirect the emission from the cannula to the camera.

主权项

1. An imaging system, comprising:
an optical fiber; a cannula configured for implantation into a subject; a mating sleeve coupling the cannula to the optical fiber; a light source coupled to the optical fiber and configured for providing optical stimulation through the optical fiber to the subject; a camera supported by the mating sleeve to capture an optical emission from the subject resulting from the optical stimulation; and a dichroic mirror secured to the mating sleeve to allow the optical stimulation to pass from the optical fiber to the cannula and to redirect the emission from the cannula to the camera.