MULTIFUNCTIONAL NANOPROBE-ENABLED CAPTURE AND EARLY DETECTION OF MICROBIAL PATHOGENS

摘要

The presently disclosed fluidic sensor system and method comprise multifunctional nanoprobe-enabled capture for early detection of chemical and/or biological pathogens in a liquid sample. This sensor system and method can be used for food and environmental monitoring.

主权项

1. A sensor system for detecting at least one chemical and/or biological pathogen in a liquid sample, the sensor system comprising:
(a) a nanoprobe comprising a plasmonic nanoparticle and a magnetic particle; (b) a flow cell comprising a channel capable of holding a liquid sample comprising at least one chemical and/or biological pathogen and the nanoprobe; (c) a magnet placed in close proximity to the flow of the liquid sample, wherein the magnet is capable of capturing the nanoprobe when the nanoprobe is bound to the at least one chemical and/or biological pathogen; and (d) an optical transducer comprising a light source and a photodetector, wherein the optical transducer is capable of detecting the nanoprobe bound to the at least one chemical and/or biological pathogen.