发明名称 |
THIENO[2,3-D]PYRIMIDIN-4-ONE DERIVATIVES AS NMDAR MODULATORS AND USES RELATED THERETO |
摘要 |
The disclosure relates thieno[2,3-d]pyrimidin-4-one derivatives as modulators of NMDA receptors and uses related thereto. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising compounds disclosed herein or pharmaceutically acceptable salts or prodrugs thereof. In certain embodiments, the compositions disclosed herein are used for managing conditions related to cognition, typically prevention or treatment of neurological conditions related to the NMDA receptor. |
申请公布号 |
WO2016081649(A1) |
申请公布日期 |
2016.05.26 |
申请号 |
WO2015US61418 |
申请日期 |
2015.11.18 |
申请人 |
EMORY UNIVERSITY |
发明人 |
TRAYNELIS, STEPHEN F.;LIEBESKIND, LANNY S.;LIOTTA, DENNIS C.;GARNIER-AMBLARD, ETHEL C.;GANGIREDDY, PAVANKUMAR REDDY |
分类号 |
A61K31/519;C07D495/04 |
主分类号 |
A61K31/519 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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