| 摘要 |
PROBLEM TO BE SOLVED: To provide: compounds used for cardiovascular diseases, ischemia, reperfusion injury, cancerous disease, pulmonary hypertension and conditions responsive to nitroxyl therapy; pharmaceutical compositions and kits comprising the compounds; and methods of using the compounds or pharmaceutical compositions.SOLUTION: The present invention provides bis-acylated hydroxylamine derivative compounds represented by formula (1), or pharmaceutically acceptable salts, hydrates or solvates thereof. (L is a bond, SOor O; Y is alkyl, aryl, heteroaryl or benzyl; and Rand Rare each independently H, alkyl, heterocycloalkyl, aryl, amino, or the like.)SELECTED DRAWING: None |
