发明名称 DISPERSIBLE TABLETS OF DEFERASIROX
摘要 PROBLEM TO BE SOLVED: To provide iron-chelating agents to remove iron from the body of a patient in need of repeating blood transfusion for thalassemia major, thalassemia intermediate and sickle cell anemia etc.SOLUTION: The dispersible tablet contains, as an active ingredient, 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid (represented by the following formula) or a pharmaceutically acceptable salt thereof in an amount of 5-40 weight% of the total weight of the tablet. For example, the pharmaceutical dispersible tablet of the invention is easy for administering to adults and children for treating thalassemia, with a pharmacologically active daily dosage of 5-40 mg/kg body weight/day, preferably 5-30 mg/kg body weight/day for children.SELECTED DRAWING: None
申请公布号 JP2016094435(A) 申请公布日期 2016.05.26
申请号 JP20150237802 申请日期 2015.12.04
申请人 NOVARTIS AG 发明人 DEFFEZ KARINE;CASSIERE JEAN-PIERRE
分类号 A61K31/4196;A61K9/00;A61K9/20;A61K31/41;A61K47/12;A61P7/06;A61P39/04 主分类号 A61K31/4196
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