AIE LUMINOGENS FOR BACTERIA IMAGING, KILLING, PHOTODYNAMIC THERAPY AND ANTIBIOTICS SCREENING, AND THEIR METHODS OF MANUFACTURING

摘要

The synthesis of fluorescent molecules with aggregation-induced emission (AIE) characteristics and application as fluorescent probes for cellular imaging, killing, and antibiotic screening, wherein the cells are bacteria or mammalian cells. The fluorescent molecules generate reactive oxygen species (ROS) upon light irradiation. A probe comprising fluorescent molecules exhibiting AIE phenomenon, wherein the probe is used for bacterial and biological study. A method of imaging and quantifying bacterial. A method of killing cells. A method of high throughput antibiotics screening and determining bacteria resistance. A method of photodynamic therapy. A method of determining critical micelle concentration.