QUINOLINE CARBOXAMIDE AND QUINOLINE CARBONITRILE DERIVATIVES AS mGluR2-NEGATIVE ALLOSTERIC MODULATORS, COMPOSITIONS, AND THEIR USE

摘要

PROBLEM TO BE SOLVED: To provide compositions effective for diseases in which the metabotropic glutamate receptor 2 negative allosteric modulator (mGluR2-NAM) receptor is involved.SOLUTION: The invention provides a compound represented by Formula (I). [The ring A is phenyl or the like; Ris -CN or the like; -L- is a bond or the like; Ris heterocycloalkyl or the like; n is an integer from 0 to 3; R(when present) is halogen or the like; and Ris H or F.]SELECTED DRAWING: None