| 主权项 |
1. A compound, the compound comprising Formula (I): wherein:
X is selected from the group consisting of hydrogen and OR2;R2 is independently selected from the group consisting of hydrogen, PO(OH)2, acetyl, COR5, CO(OR5), CO(NR5R6), CO(CH2)nNR5R6, hydrocarbyl and substituted hydrocarbyl;n is an integer from 1 to 10;Z is O;Y is selected from the group consisting of O, CH(OH), CH(OR5), CHNR5R6, CH2, S, and NR5;R1 is selected from the group consisting of CH3, CF3, halogen, Cl, F, Br, I, OH, NH2, NR5R6, OCH3, CO2CH3, CONHCH3, alkyl, cyclopropyl, OR5, CO2R5, CONR5R6, hydrocarbyl, and substituted hydrocarbyl;R3 is selected from the group consisting of formula (IA) and formula (IB): A is independently selected from the group consisting of CR5 and N;G is independently selected from the group consisting of S, NR5 and O;a is an integer from 1 to 4;R4 is selected from the group consisting of CONHCH3, COOCH3, COOH, CON R5, CONH(heterocycle), heterocycle, H, alkyl, cyclopropyl, aryl, OR5, NR5R6, NR5COR6, NR5COOR6, NR5CONR6, NR5SO2R6, COR5, SO2R5, halogen, CN, NO2, COOR5, CONR5R6, NCOR7, NCONR7, NCOOR7, SO2NR5R6, and NHSO2R7, or when a is greater than or equal to 2, R4 may optionally form an optionally substituted cycloalkyl, aryl or heterocyclo 5 or 6 membered ring;R5 is selected from the group consisting of H and an optionally substituted alkyl, aryl, heterocycle, and cycloalkyl;R6 and R7 are selected from the group consisting of an optionally substituted alkyl, cycolalkyl, aryl, and heterocycle. |
