SYSTEM GENERATING A CONSTRAINT FIELD, AND MEDICAL DEVICE IMPLEMENTING THE SAME

摘要

Disclosed is a system including (1) an injection device including injectable magnetizable nanoparticles and a component for injecting the same, and (2) a unit for applying a constraint physically and/or mechanically to a tumor associated to an neoangiogenic network where, after having been injected, the particles are retained. Also disclosed is a method for treating tumors, especially tumors associated with a neoangiogenic network, including the steps of: injecting a composition including magnetizable nanoparticles; optionally performing imaging using an imaging device to detect a concentration of nanoparticles retained in the neoangiogenic network; and applying a contact-free constraint onto a tumor in vivo, by a gradient of magnetic field and the application being directed to the tumor region.

主权项

1. Medical system comprising (1) injectable magnetizable nanoparticles and means for injecting the same, and (2) means for applying a physical and/or mechanical constraint to a tumor associated to a neoangiogenic network where, after having been injected, the particles are retained, said means for applying a physical and/or mechanical constraint being a generator releasing a gradient of magnetic field; and
wherein the system is neither a cell construct nor an implant; the system is not used for treating a tumor by pharmaceutical means; the particles are not used such as drug carrier or as imaging agent.