发明名称 |
A method for profiling kinase inhibitors |
摘要 |
5 The present invention is concerned with method for pharmacologically profiling compounds using an array of substrates, in particular kinase substrates, immobilized on a porous matrix. This method was found particular useful in the prediction of drug response, i.e. to enable the distinction between responders and non-responders in the treatment of cells, tissues, organs or warm-blooded animals with the compound to be 10 tested, and in compound differentiation. |
申请公布号 |
AU2014202643(B2) |
申请公布日期 |
2016.05.26 |
申请号 |
AU20140202643 |
申请日期 |
2014.05.15 |
申请人 |
JANSSEN PHARMACEUTICA NV |
发明人 |
VERSELE, MATTHIAS LUC AIME;PERERA, TIMOTHY PIETRO SUREN;TALLOEN, WILLEM JAN-PAUL EDMOND;HOUTMAN, RENE;RUIJTENBEEK, ROBBY |
分类号 |
C12Q1/48;G01N33/50;G01N33/68 |
主分类号 |
C12Q1/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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