GENERATION OF KERATINOCYTES FROM PLURIPOTENT STEM CELLS AND MAINTENANCE OF KERATINOCYTE CULTURES

摘要

Provided herein are methods for the generation of functional keratinocyte stem cells that are differentiated directly from human ESCs/iPSCs in a chemically defined serum-free cell culture system, as well as cells derived therefrom and methods of use thereof. Also provided are methods for culturing primary keratinocytes.