发明名称 |
Methods and systems for analysis of organ transplantation |
摘要 |
Disclosed herein are methods of detecting, predicting or monitoring a status or outcome of a transplant in a transplant recipient. In some aspects, a method for detecting or predicting a condition of a transplant recipient comprises a) obtaining a sample, wherein the sample comprises one or more gene expression products from the transplant recipient; b) performing an assay to determine an expression level of the one or more gene expression products from the transplant recipient; and c) detecting or predicting the condition of the transplant recipient by applying an algorithm to the expression level determined in step (b), wherein the algorithm is a classifier capable of distinguishing between at least two conditions that are not normal conditions, and wherein one of the at least two conditions is transplant rejection or transplant dysfunction. |
申请公布号 |
GB2532672(A) |
申请公布日期 |
2016.05.25 |
申请号 |
GB20160003464 |
申请日期 |
2014.09.09 |
申请人 |
The Scripps Research Institute |
发明人 |
Daniel Salomon;Sunil M Kurian;Steven Head;Michael M Abecassis;John J Friedewald;Josh Levitsky |
分类号 |
C12Q1/68;G06F19/00;G06F19/18 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|