ACTIVIN-ACTRII ANTAGONISTS AND USES FOR TREATING BONE AND OTHER DISORDERS
摘要
Provided herein are methods for the treatment of bone disorders that are associated with kidney disease wherein the methods comprise administration of Activin-ActRIIA inhibitors to a subject in need of the treatment. Also provided herein are methods and compositions for the treatment of low turnover bone disorders wherein the methods comprise administration of Activin-ActRIIA inhibitors to a subject in need of the treatment. Further provided herein are compositions for the treatment of bone disorders that are associated with kidney disease and compositions for the treatment of low turnover bone disorders and vascular calcification.
申请公布号
EP2914277(A4)
申请公布日期
2016.05.25
申请号
EP20130851864
申请日期
2013.11.01
申请人
CELGENE CORPORATION;WASHINGTON UNIVERSITY;SLOAN, VICTOR SCHORR;HRUSKA, KEITH;FANG, YIFU
发明人
SLOAN, VICTOR, SCHORR;HRUSKA, KEITH;FANG, YIFU;SUNG, VICTORIA;STEVENS, RANDALL;SMITH, WILLIAM