发明名称 FORMULATION FOR BISPECIFIC T-CELL ENGAGERS (BITES) T(BITES)
摘要 The present invention relates to stable pharmaceutical compositions which contain polypeptides having at least two antigen-binding domains and are especially suited for subcutaneous administration. The invention provides liquid compositions which minimize the formation of undesired polypeptide aggregates (dimers and/or multimers). The present invention further provides a method for minimizing the aggregation of polypeptides having antigen-binding domains in liquid compositions.
申请公布号 HK1211215(A1) 申请公布日期 2016.05.20
申请号 HK20150112055 申请日期 2015.12.08
申请人 BAYER PHARMA AKTIENGESELLSCHAFT 发明人 OLBRICH, CARSTEN;BUNTE, THOMAS;WINTER, JONAS;PETERS, JRG;TRILL, THOMAS
分类号 A61K;A61P;C07K 主分类号 A61K
代理机构 代理人
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