发明名称 ASSAY AND METHOD
摘要 The present invention relates to an assay for use in a method of determining the oral health status of a canine animal by identifying certain bacteria present or absent in a sample taken from the animal, and applying the information set out herein for each identified bacteria to statistical models in order to determine the oral health status of the animal.
申请公布号 US2016138089(A1) 申请公布日期 2016.05.19
申请号 US201414898149 申请日期 2014.06.13
申请人 MARS, INCORPORATED 发明人 Harris Stephen James;Coates Matthew;Gibbs Matthew Ronald
分类号 C12Q1/68;A61Q11/00;A61K8/02;G06F19/18;G06F19/24 主分类号 C12Q1/68
代理机构 代理人
主权项 1. An assay for use in a method for determining the oral health status of a canine animal, the assay comprising means for identifying at least two bacteria selected from the list consisting of:Peptostreptococcaceae_XIII_[G-1]_sp._COT-030Peptostreptococcaceae_XIII_[G-2]_sp._COT-077Capnocytophaga_canimorsusMoraxella_sp._COT-017Escherichia_coliFusobacterium_sp._COT-189Selenomonas_sputigena_COT-342Proprionibacterium_sp._COT-365Treponema_sp._COT-200Corynebacterium_sp._cluster 88112Erysipelotrichaceae_[G-3]_sp._COT-302Filifactor_sp._COT-163Lachnospiraceae_XIVa_[G-3]_sp.Filifactor_sp._COT-064Neisseria_sp._COT-049Neisseria_weaveri_COT-269Peptostreptococcaceae_XI_[G-6]_sp._COT-067Capnocytophaga_canimorus_COT-235Porphyromonas_macacae_COT-192Treponema_sp._COT-351Lachnospiraceae_XIVa_[G-6]_sp._COT-161Cardiobacterium_sp._COT-176Pasteurellaceae_sp._COT-271Peptostreptococcaceae_XI_[G-7]_sp._COT-155Schwartzia_sp._COT-063Wolinella_succinogenesActinobaceria_sp._COT-376Clostridiales_[F-2.G-1]_sp._COT-100_PO005Clostridiales_III_[G-3]_sp._COT-388Desulfovibrionales_sp._COT-009Peptostreptococcaceae_XI_[G-3]_sp._COT-034Porphyromonas_gulae_I_COT-052Treponema_sp._COT-198ParvimonasPeptostreptococcusMoraxellaFilifactorSchwartziaTreponemabacterium_cp04.17CapnocytophagaAtopobiumPhascolarctobacteriumGlobicatellaPrevotellaCurtobacteriumGranulicatellaSolobacterium provided that at least one of the bacteria is selected from the list consisting ofPeptostreptococcaceae_XIII_[G-1]_sp._COT-030Peptostreptococcaceae_XIII_[G-2]_sp._COT-077Capnocytophaga_canimorsusEscherichia_coliFusobacterium_sp._COT-189Selenomonas_sputigena_COT-342Proprionibacterium_sp._COT-365Treponema_sp._COT-200Corynebacterium_sp._cluster 88112Erysipelotrichaceae_[G-3]_sp._COT-302Filifactor_sp._COT-163Lachnospiraceae_XIVa_[G-3]_sp.Filifactor_sp._COT-064Neisseria_sp._COT-049Peptostreptococcaceae_XI_[G-6]_sp._COT-067Capnocytophaga_canimorus_COT-235Porphyromonas_macacae_COT-192Treponema_sp._COT-351Lachnospiraceae_XIVa_[G-6]_sp._COT-161Cardiobacterium_sp._COT-176Peptostreptococcaceae_XI_[G-7]_sp._COT-155Schwartzia_sp._COT-063Wolinella_succinogenesActinobaceria_sp._COT-376Clostridiales_[F-2.G-1]_sp._COT-100_PO005Clostridiales_III_[G-3]_sp._COT-388Desulfovibrionales_sp._COT-009Peptostreptococcaceae_XI_[G-3]_sp._COT-034Treponema_sp._COT-198ParvimonasFilifactorSchwartziabactedum_cp04.17CapnocytophagaAtopobiumPhascolarctobacteriumGlobicatellaCurtobacteriumGranulicatellaSolobacterium in a sample taken from the animal, and applying the information set out in table 5 for each identified bacteria to statistical models in order to determine the oral health status of the animal.
地址 Mclean VA US