发明名称 CRYSTALLINE SOLVATES AND COMPLEXES OF (1S) -1, 5-ANHYDRO-1-C-(3-((PHENYL)METHYL)PHENYL)-D-GLUCITOL DERIVATIVES WITH AMINO ACIDS AS SGLT2 INHIBITORS FOR THE TREATMENT OF DIABETES
摘要 Abstract The present invention relates to crystal forms of the compound of the formula I including complexes tmeof wherein the complex is formed as a co-crystal forn with proline or phenylaianine. The invention also discloses processes of ornming the crystal fons of formMla I and methods of treating diseases such as diabetes, glucose intolerance, insulin resistance and other conditions using such structures. OEt HO"'O
申请公布号 AU2014268177(B2) 申请公布日期 2016.05.19
申请号 AU20140268177 申请日期 2014.11.26
申请人 ASTRAZENECA AB 发明人 GOUGOUTAS, JACK Z.;LOBINGER, HILDEGARD;RAMAKRISHNAN, SRIVIDYA;DESHPANDE, PRASHANT P.;BIEN, JEFFREY T.;LAI, CHIAJEN;WANG, CHENCHI;RIEBEL, PETER;GROSSO, JOHN ANTHONY;NIRSCHL, ALEXANDRA A.;SINGH, JANAK;DIMARCO, JOHN D.
分类号 C07H7/04;A61K31/70;A61P3/10 主分类号 C07H7/04
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