MANUFACTURING METHOD OF HYDROXY ADAMANTANE CARBOXYLIC ACID COMPOUND

摘要

PROBLEM TO BE SOLVED: To provide a method for easier manufacturing a hydroxy adamantane carboxylic acid at higher yield.SOLUTION: There is provided a manufacturing method of 3-hydroxy adamantane-1-carboxylic acid represented by the formula (2) including Process 1: adamantanol represented by the formula (1) and carbon monoxide or a carbon monoxide source are mixed in a sulphuric acid solution with concentration of 90 mass% or more and Process 2:nitrate is added to the resulting solution.SELECTED DRAWING: None