| 发明名称 |
PREPARATION OF (S,S)-SECOISOLARICIRESINOL DIGLUCOSIDE AND (R,R)-SECOISOLARICIRESINOL DIGLUCOSIDE |
| 摘要 |
The invention relates to processes for preparing (S,S)-secoisolariciresinol diglucoside and (R,R)-secoisolariciresinol diglucoside and compositions comprising the same. |
| 申请公布号 |
US2016137682(A1) |
申请公布日期 |
2016.05.19 |
| 申请号 |
US201414897181 |
申请日期 |
2014.06.10 |
| 申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA ;THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
CHRISTOFIDOU-SOLOMIDOU Melpo;NICOLAOU Kyriacos C.;VALIULIN Roman A.;SIMMONS Nicholas;HERETSCH Philipp M. |
| 分类号 |
C07H15/18;C07C67/343;C07C67/31;C07C67/303;C07H15/203;C07C41/18 |
主分类号 |
C07H15/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A process for preparing a compound of formula ((S,S)-SDG-1)the process comprising:
(a) reacting a compound of formula (6)with a compound of formula (7)to prepare a compound of formula ((S,S)-S3) (b) cleaving benzyl ethers of the compound of formula ((S,S)-S3), followed by a separation procedure to prepare a compound of formula ((S,S)-8)and
(c) deprotecting the compound of formula ((S,S)-8) to prepare the compound of formula ((S,S)-SDG-1). |
| 地址 |
Philadelphia PA US |
